PBMC humanization kits for NCG mouse models facilitate infectious disease and immuno-oncology research. HemaCare and Charles River Laboratories Announce Strategic Partnership to Accelerate Drug ...

Charles River Laboratories is incorporating HemaCare’s human peripheral blood mononuclear cells (PBMCs) into its NCG mouse model, ... and a recent Novartis CAR-T study also used its PBMC cells.

The humanized portfolio will add two PBMC humanized models, HuPBMC NCG-B2m-KO and HuPBMC NCG-MHC-dKO, to support studies of immune responses, tumor growth, and infectious diseases.