The STING pathway also activates the NF-κB signaling cascade, further promoting inflammation. The STING pathway's role in NAFLD progression is multifaceted. High-fat diet-induced NAFLD has been ...

Researchers have now found a signaling pathway in cells that play an important role in the development of fatty liver disease. In Switzerland, about every tenth adult suffers from morbid obesity.

This effectively suppresses the excessive activation of a cellular signaling pathway known as ... MOAP-1 in the development of non-alcoholic fatty liver disease (NAFLD), which is a rapidly ...

The results of this study demonstrate that HO-1 helps reduce hepatic fibrosis associated with NAFLD by modulating the SIRT1/TGF-β/Smad3 signaling pathway. Insights into the interactions between ...

Scientists discovered a novel signaling pathway in liver cells, leading to a treatment for fibrosis. A healthy liver filters all the blood in your body, breaks down toxins and digests fats.

The researchers found that FGF21 activates a signaling pathway in the brain that triggers changes in nerve activity directed ...

A pioneering research study published today in Cell Metabolism details how the hormone FGF21 (fibroblast growth factor 21) can reverse the effects of fatty liver disease in mice. The hormone works ...

will present new data from Axcella’s AXA1125 liver program at the Integrated Pathways of Disease in NASH and NAFLD Keystone Symposium, taking place January 20-24, 2019 in Sante Fe, NM.