Biocytogen Pharmaceuticals (Beijing) Co., Ltd. (“Biocytogen”, HKEX: 02315) announced United States Patent and Trademark Office (USPTO) patent grant for independently developed RenLite® fully human ...

Cardiac-specific myosin light chain kinase (cMLCK), encoded by MYLK3, regulates cardiac contractility through phosphorylation of ventricular myosin regulatory light chain. However, the ...

Vatche and Tamar Manoukian Division of Digestive Diseases, David Geffen School of Medicine, University of California Los Angeles (UCLA), Los Angeles, CA, United States To determine whether the ...

Smooth muscle myosin light chain kinase (smMLCK) is a member of a diverse group of serine/threonine kinases that feature cytoskeletal association. Its catalytic activity is triggered by a ...

Thank you for submitting your article "Mechanical Force as a Functional Regulator in Smooth Muscle Myosin Light Chain Kinase" for consideration by eLife. Your article has been favorably evaluated by ...

1 Central Laboratory, The First Affiliated Hospital, Dalian Medical University, Dalian, China 2 Laboratory Animal Center, Dalian Medical University, Dalian, China Myosin light chain kinase (MLCK) ...

We used phosphorylation of the myosin regulatory light chain (cRLC) by the cardiac isoform of its specific kinase to elucidate mechanisms of thick filament-mediated contractile regulation in ...

Myosin light chain (MLC) phosphorylation determines vascular contractile status. In addition to the classic Ca 2+-dependent MLC kinase (MLCK), another unidentified kinase(s) also contributes to MLC ...

Here, we show that phosphorylation of MEF2C on T 80 by skeletal myosin light chain kinase (skMLCK) enhances skeletal and not cardiac myogenesis. A phosphorylation‐deficient MEF2C mutant (MEFT80A) ...