Objective Intestinal barrier loss is a Crohn’s disease (CD) risk factor. This may be related to increased expression and enzymatic activation of myosin light chain kinase 1 (MLCK1), which increases ...

“Chain of Light,” an album of four qawwalis the Pakistani singer recorded in 1990, are arriving after being discovered in the vaults of Peter Gabriel’s label.

Two myosin light chain (MLC) kinase (MLCK) proteins, smooth muscle (encoded by mylk1 gene) and skeletal (encoded by mylk2 gene) MLCK, have been shown to be expressed in mammals. Even though phosphory ...

Cardiac-specific myosin light chain kinase (cMLCK), encoded by MYLK3, regulates cardiac contractility through phosphorylation of ventricular myosin regulatory light chain. However, the ...

A highly sophisticated and adaptive interplay between modulation of myosin II function by light chain phosphorylation and environmentally controlled formin availability, is critical for a successful ...

Most notably we observed that AFTPH co-localized with myosin light chain kinase (MLCK) and attenuated cellular MLCK activity as observed by phospho- myosin light chain 2 (pMLC2) western blots.

The expression and function of myosin light chain kinase in aneurysms were examined. We found that 180 proteins were differentially expressed between the aneurysm and control samples, among which 88 ...

Atomic force microscopy based single-molecule force spectroscopy of smooth muscle myosin light chain kinase strongly indicates the existence of a mechanically triggerable activation pathway analogous ...

Here we present a bioinformatics analysis of proteomics data obtained for larvae of four different species of fly to assess the homology of tropomyosin, arginine kinase and myosin light chain with the ...

Contraction of heart muscle is triggered by calcium binding to the actin-containing thin filaments but modulated by structural changes in the myosin-containing thick filaments. We showed that ...

Myosin light chain (MLC) phosphorylation determines vascular contractile status. In addition to the classic Ca 2+ -dependent MLC kinase (MLCK), another unidentified kinase (s) also contributes to MLC ...