Primary cultures of cardiac ventricular myocytes from ... EcoR1 fragment of constitutively active rabbit skeletal muscle myosin light chain kinase (tSkMLCK, a gift of J.T.Stull) was subcloned ...

In the cells of the cardiac ... muscle. The SERCA2a is controlled by phospholamban, a regulatory inhibitor protein which binds SERCA2a. When phospholamban is phosphorylated by CaMKII and protein ...