The adaptor proteins MyD88 and the associated protein IL-1R ... IL-33 stimulation may include phosphorylation of extracellular signal-regulated kinase (ERK) 1/2, p38 MAPK, JNKs and activation ...

Identifying proteomic signatures of insulin resistance in fasting muscle offers insights for personalized type 2 diabetes ...

Pro-inflammatory signaling molecules in MS cause problems with the growth and development of myelin-making cells in the brain ...

A study conducted by researchers at the Center for Cell-Based Therapy (CTC) highlights key proteins and signaling pathways ...

where calcium imbalance and impaired synaptic signaling are key features. This newly identified GPR158–PLCXD2 axis offers insight into how synaptic structure and receptor content are regulated ...

Insects, which comprise over half of all known living organisms, play critical roles in ecosystems as pollinators, decomposers, and vectors of diseases.

Inflammation plays a crucial role in the development of various diseases, including cancer, allergic diseases, such as asthma, and cardiovascular diseases, such as atherosclerosis and heart failure.

Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly regulated processes in eukaryotic cells. Conventionally, proteins that are ...

How BCR and CD40 signaling are integrated quantitatively to jointly determine B-cell fate decisions remains unclear. Here, we ...