Millions of individuals rely on effective medications to manage diseases like cancer and diabetes. For those with chronic ...

Multiple steps are involved in the pathogenesis of chronic lymphocytic leukemia (CLL ... such as mutations in B-cell receptors (BCRs) and dysregulation of messenger RNA. 1 CLL is a hematologic ...

This review discusses the dual role mitophagy plays in AML survival ... characterized by the abnormal proliferation of partially-differentiated hematopoietic stem cells (HSCs) (1). Although there are ...

Study finds surprising way that genetic mutation causes Huntington's disease, transforming understanding of the disorder Researchers studying brain cells from Huntington's patients show that the ...

Introduction: Bryostatin-1, a potent agonist of the protein kinase C ... 1 directly impacts exhausted CD8+ T cells. Methods: PBMCs from people with HIV (PWH) were treated with bryostatin-1 and tracked ...