Credit: Nature Communications (2025). DOI: 10.1038/s41467-025-56888-6 The structure showed 12 transmembrane helices in two pseudo-symmetric bundles and two periplasmic subdomains.

The structure showed 12 transmembrane helices in two pseudo-symmetric bundles and two periplasmic subdomains. Experiments showed that the coiled-coil domain, whose predicted model extends from one of ...

More information: Yun Zhu et al, In situ structure of the mouse sperm central apparatus reveals mechanistic insights into asthenozoospermia, Cell Research (2025). DOI: 10.1038/s41422-025-01135-2 ...

An interaction between two proteins points to a molecular basis for memory. But how do memories last when the molecules that ...

News & Views Published: September 2008 Insights into PPARγ from structures with endogenous and covalently bound ligands Kendall W Nettles Nature Structural & Molecular Biology 15, 893–895 (2008 ...

Here we use cryogenic electron microscopy to determine the structure of TbAQP2 from Trypanosoma brucei, bound to either the substrate glycerol or to the sleeping sickness drugs, pentamidine or ...

Researchers have found a new way to optimise the design molecular motors, bringing us one step closer to making synthetic molecular machines a reality ...

Overall structure The structure of HO-1 with bound substrate, heme, has been refined in crystal form C to an R factor of 0.213 and free R factor of 0.265 at 2.08 Å resolution. There are two ...

The review introduces the molecular subtypes of breast cancer and outlines how altered amino acid metabolism supports tumor ...

Aliphatic carbonyls widely exist in source emissions and the atmosphere, serving as secondary organic aerosol (SOA) precursors. Molecular structure including carbon number and functional groups ...

Polydiacetylenes (PDAs) possess dramatic chromatic transitions, which can be exploited to make stimuli-responsive sensors. Key to developing robust sensors is understanding the changes in molecular ...