Many fundamental processes of life, and their synthetic counterparts in nanotechnology, are based on the autonomous assembly ...

Mitotic spindles use an elegant bipolar architecture to segregate duplicated chromosomes with high fidelity. ... We describe a physical model that exhibits de novo bipolar spindle formation.We began ...

Slicing mitotic spindle with lasers, nanosurgeons unravel old pole-to-pole theory. ScienceDaily . Retrieved May 28, 2025 from www.sciencedaily.com / releases / 2012 / 04 / 120426135124.htm ...

Cambridge, Mass. - April 26, 2012 - The mitotic spindle, an apparatus that segregates chromosomes during cell division, may be more complex than the standard textbook picture suggests, according ...

To better understand the role of kinesin-8 proteins in mitosis, we have studied the effects of deletion of the fission-yeast kinesin-8 proteins Klp5 and Klp6 on chromosome movements and spindle length ...

In research published October 1 in Developmental Cell, scientists at The Rockefeller University reveal new insights into the mechanical forces that govern elements of the mitotic spindle formation ...

During cell division, the motor protein kinesin-5 hastens or retards microtubule sliding in the mitotic spindle, imparting forces that scale with the degree of microtubule overlap.

Many millions of times per day, football-shaped structures called mitotic spindles form within the body’s cells as they prepare to divide. The process is routine but mysterious, as the micro-mechanics ...