The antimitotic properties of parthenolide, a natural compound with known anticancer activity, have been largely ...

Spindle assembly and function require localized regulation ... distinct sub-populations of microtubules exist within mitotic spindles: first, kinetochore microtubules that terminate end-on in ...

regulation of MT overlaps is important for mitotic spindle function and cytokinesis. We are studying the density of motors on antiparallel microtubule overlaps and subsequent length regulation of the ...

Most vertebrates contain two Sgo proteins, but their specific functions are not always clear ... of at least one key substrate for bipolar spindle assembly, the microtubule depolymerizing kinesin MCAK ...

Centromeres, specialized regions located at the center of chromosomes, are critical for ensuring proper cell division. During ...

Northwestern Medicine scientists have uncovered new details about how poxvirus hijacks its host's protein synthesis machinery ...

Find more information on the Altmetric Attention Score and how the score is calculated. During mitosis, phosphorylation of spindle associated proteins is a key regulatory mechanism for spindle ...

† Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan ‡ Graduate School of Pharmaceutical Sciences, University of Shizuoka, Suruga-ku, Shizuoka 422-8526, ...

Departments of Cell Biology [C. W. C., R. F. H., P. J. S.] and Molecular Genetics [Y. S.], University of Cincinnati College of Medicine, Cincinnati, Ohio 45267, and ...