The mitotic spindle (white) begins to form outside the cell's nucleus. This image is linked to the following Scitable pages: Replication and Distribution of DNA during Mitosis. Cell division, the ...

In research published October 1 in Developmental Cell, scientists at The Rockefeller University reveal new insights into the mechanical forces that govern elements of the mitotic spindle formation ...

Many millions of times per day, football-shaped structures called mitotic spindles form within the body's cells as they prepare to divide. The process is routine but mysterious, as the micro ...

In research published October 1 in Developmental Cell, scientists at The Rockefeller University reveal new insights into the mechanical forces that govern elements of the mitotic spindle formation ...

Many millions of times per day, football-shaped structures called mitotic spindles form within the body’s cells as they prepare to divide. The process is routine but mysterious, as the micro-mechanics ...

Bipolar spindles form from a monopolar initial condition; this is the most fundamental construction problem that the spindle must solve. We describe a physical model that exhibits de novo bipolar ...

The mitotic spindle, an apparatus that segregates chromosomes during cell division, may be more complex than the standard textbook picture suggests. ... the formation of the spindle.

During cell division, the motor protein kinesin-5 hastens or retards microtubule sliding in the mitotic spindle, imparting forces that scale with the degree of microtubule overlap.

Kinesin-5-independent mitotic spindle ... We demonstrate that cut7Δpkl1Δ spindle bipolarity requires the microtubule antiparallel bundler PRC1/Ase1 to recruit CLASP/Cls1 to stabilize microtubules.