SCF (complex of SKP1, CUL1 and F-box protein) complexes are ubiquitin ligases that bind to protein substrates and target them for ubiquitylation and subsequent degradation by the proteasome.

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The membrane-bound aggregates were then cleared as cells progressed through mitosis and cytokinesis. Aggregate clearance depended on Hsp70 family chaperones in the ER, particularly BiP, and ...

A weak loss‐of‐function (lf) allele of ect‐2 (also known as let‐21), which encodes the likely PBL/ECT2 orthologue, has been shown to enhance the cytokinesis defect during the first embryonic cell ...