We report 5-year safety, efficacy and radiographic outcomes of sarilumab from NCT01061736 and the open-label extension (EXTEND; NCT01146652), in which patients received sarilumab 200 mg every 2 weeks ...

Patients without need for rapid symptom relief might need only methotrexate. However, the open-label trial had some key limitations, cautioned Baughman and Lower. The baseline impairment in FVC ...

The study, “Intrathecal methotrexate in progressive multiple sclerosis: a phase 1 open-label study with long-term follow-up,” was published in the Journal of Neurology. Methotrexate is an anti ...

including methotrexate and warfarin. Before starting pantoprazole, talk with your healthcare professional about all your medications. Doing so can help them plan your treatment accordingly or adjust ...

An off-label prescription drug has been shown to ... "Leucovorin is FDA-approved to reduce the toxic effects of high-dose methotrexate in cancer treatment and to prevent or treat certain types ...

Objective To evaluate long-term clinical, functional and radiographic outcomes in an open-label extension (OLE) study in patients with rheumatoid arthritis (RA) receiving adalimumab monotherapy or ...

Talk to your doctor if you are breastfeeding or intend to breastfeed. Methotrexate passes into breast milk and should not be taken when breastfeeding. Always read the pharmacist's label to check the ...

eBlizard Institute, Centre for Genomics and Child Health, Faculty of Medicine and Dentistry, Queen Mary University of London, London, UK fDepartment of Inflammation and Immunology, Imperial College ...

The VESPER (French Genito-Urinary Tumor Group and French Association of Urology V05) trial reported improved 3-year progression-free survival with dose-dense methotrexate ... VESPER was an open-label, ...

The FDA and Health Canada "should also consider issuing warning labels to inform prescribers of the study's findings," the researchers wrote. Methotrexate is commonly prescribed for rheumatoid ...