Other major telophase events, such as chromosome decondensation, nuclear envelope formation and the initiation of cytokinesis, also depend on Cdk-substrate dephosphorylation during late anaphase ...

Cell division requires the regulation of karyokinesis and cytokinesis, which includes an essential role of the achromatic spindle. Although the functions of centrosomes are well characterised in ...

Mitosis occurs in five stages: prophase, prometaphase, metaphase, anaphase and telophase.

Stabilization of microtubule plus end-directed kinesin CENP-E at the metaphase kinetochores is important for chromosome alignment, but its mechanism remains unclear. Here, we show that CKAP5, a ...

APC is the key E3 ubiquitin ligase that promotes metaphase-anaphase transition. Although the phosphorylation status of some substrates determines their recognition by APC and influences the precise ...