The prevalence of diabetes mellitus (DM) increased by 49% between 1990 and 2000, reaching nearly epidemic proportions. In 2010, DM (type 1 or 2) was estimated to affect nearly 30% (10.9 million ...

OBJECTIVE: To examine and compare in vitro basal and insulin-stimulated glucose uptake in human omental and subcutaneous adipose tissue derived from lean, overweight or obese individuals, and in ...

In affected people, insulin is unable to facilitate the uptake of glucose through tissues and organs, leading to an increase in blood glucose (chronic hyperglycaemia).

In affected people, insulin is unable to facilitate the uptake of glucose through tissues and organs, leading to an increase in blood glucose (chronic hyperglycemia).

Insulin is one of those vital hormones and is produced by your pancreas. It regulates how your body uses glucose, a form of sugar that’s created when your body breaks down the carbohydrates you eat.

One way insulin does that is to accelerate the removal of glucose from blood and into muscle and fat cells. Key aspects of the mechanism for insulin to stimulate this glucose uptake remain to be ...

Since insulin is the hormone governing glucose uptake, insulin resistance often results in progressively increasing blood glucose levels, substantially increased prediabetes and type 2 diabetes ...

Insulin is a vital hormone that controls numerous processes in the body—from blood glucose (blood sugar) regulation to cell growth. Impaired insulin action is a major factor in the development ...

The balance between the secretion and action of hormones is essential for the body to function properly. Thus, the secretion of several hormones, including insulin, varies over a 24-hour period ...

Some mammals are capable of hibernating during periods of low food availability in an effort to conserve energy and survive.

As plasma glucose levels fall, the compromised physiologic defenses include failure of insulin levels to diminish (in the absence of endogenous insulin secretion, circulating insulin levels are a ...