“Anticholinergics are associated with numerous adverse outcomes in older adults; therefore, it is essential for clinicians to avoid their use when possible, prescribe the lowest effective dose, and ...

Mechanism of action articles from across Nature Portfolio Mechanism of action describes the process by which a molecule, such as a drug, functions to produce a pharmacological effect. A drug’s ...

We show that raised concentrations of extracellular calcium ions shift the preferred mode of exocytosis to the kiss-and-run mechanism in a calcium-concentration-dependent manner.

Recent studies have shown that both synthetic and naturally occurring biological molecules can be efficacious in the treatment of brain disorders. While ...

This meta-analysis from two nationwide cohorts indicates that SSRI and SNRI augmentation therapies for people with ...