Integrated network pharmacology and molecular dynamics suggest potential mechanisms involving AKT1, EGFR, and pathways like PI3K-Akt and MAPK. While further experimental validation is needed, these ...

Psoriasis Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.

Plants produce an astonishing variety of chemical substances. Most of these metabolites are involved in chemical ...

An investigational oral targeted therapy, zipalertinib (CLN-081), demonstrated meaningful tumor responses and a manageable ...

A research team at The University of Tokyo has discovered that inhalational anesthetics activate a protein called type 1 ryanodine receptor (RyR1), which contributes to the induction of general ...

Antimalarial Drugs: Modes of Action and Mechanisms of Parasite Resistance Ingrid B Müller; John E Hyde Disclosures Future Microbiol. 2010;5 (12) 0 ...

Degenerative Disc Disease Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action ...

The defects in molecular and cellular processes that constitute the triggers of specific pathologies are referred to as mechanisms of disease. Research in this area is vital for designing ...

E-scooters, motorbikes, drugs, cash and a chainsaw among items seized during garda 'Day of Action' Gardai conducted 40 searches on Tuesday as part of a Day Of Action targeting electric motorbikes ...

Antimalarial Drugs: Modes of Action and Mechanisms of Parasite Resistance Ingrid B Müller; John E Hyde Disclosures Future Microbiol. 2010;5 (12) 0 Atovaquone: Rational Targeting of the Mitochondrion ...

South Scotland MSP, Colin Smyth, has called for action to bolster support for drug rehabilitation and treatment following the release of the statistics. Across Scotland, 308 suspected drugs deaths ...