We also show that both Cbl and Gab1 enhance Met-induced activation of another MAP kinase cascade, the ERK pathway, in a Crk-independent manner. Taken together, our studies demonstrate a previously ...

Mitogen-activated protein kinase (MAPK) is an integral component ... To investigate the role of the MAPK cascade in mammalian learning, we determined if learning is associated with activation ...

Issued on behalf of Oncolytics Biotech Inc. VANCOUVER – Baystreet.caNews Commentary – As traditional research institutions ...

Cascade track and field athlete Liam Brewer is the winner of the Maps Credit Union high school boys Athlete of the Week, as voted by Statesman Journal readers. More: Cascade track and field ...

The Center for Healthcare Quality and Payment Reform has identified over 300 rural hospitals at "immediate risk" of closure, as shown in the map above. The states that could see the highest number ...

BACKGROUND: Dilated cardiomyopathy (DCM) is substantially influenced by genetic factors. Sarcomere function is intricately associated with other organelles, particularly the reciprocal regulation ...

Night - Mostly clear with a 37% chance of precipitation. Winds variable at 6 to 9 mph (9.7 to 14.5 kph). The overnight low will be 42 °F (5.6 °C). Partly cloudy with a high of 65 °F (18.3 °C ...

Night - Mostly clear with a 40% chance of precipitation. Winds variable. The overnight low will be 37 °F (2.8 °C). Mostly cloudy with a high of 65 °F (18.3 °C) and a 43% chance of ...

The AMP-activated protein kinase (AMPK) system acts as a sensor of cellular energy status that is conserved in all eukaryotic cells. It is activated by increases in the cellular AMP:ATP ratio caused ...

Despite the strong link between animal development and adult lifespan, how developmental programs influence longevity remains poorly understood. Here, we show that mutants of the insect neuropeptide ...

Abstract: This paper analyzes the characteristics of sequences generated using cascade chaotic maps employing two or three seed maps. We begin by comparing their Lyapunov exponents and also propose a ...

This study presents the important finding that lysosomal damage triggers inflammatory signaling through ubiquitination and the TAB-TAK1-IKK-NF-kB axis. The data obtained from the unbiased ...