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Model of the malaria parasite-infected RBC membrane. Credit: Dr Eric Hanssen, Mr Yao Zhang Infection with parasites changes the shape of RBCs resulting in cells becoming stuck in brain blood vessels.
The fight against malaria faces many obstacles, including funding cuts. But it remains far cheaper to prevent the disease than to treat it.
Malaria which is caused by Plasmodium parasite is one of the diseases that can cause death in patients. Detection of plasmodium parasites on the Red Blood Cell (RBC) image can help diagnose malaria ...
Table 2. Functional forms commonly used to describe uninfected RBC (red blood cell) clearance during malaria infections. Critically, the robustness of model-derived inferences about the disease and ...
Red blood cell variants protect African children from severe falciparum malaria. However, their individual and interactive effects on mild disease and parasite density, and their modification by ...
There are many reasons that malaria is so persistent in Africa. Four of them are poverty, human movement, resistance and climate change.
image image As first line of defense against severe malaria, neutrophils recognize specific PfEMP1 molecules on the infected erythrocyte via ICAM‐1. This ligand‐receptor interaction leads to efficient ...
Genetic analysis identifies an enzyme of the malaria parasite that is required to seal its host red blood cell membrane upon invasion, a key requirement of this important intracellular pathogen.
In the present review, we have summarized the significance of both the S1P pools in the context of malaria, and how the RBC content of S1P can be channelized in better ways for its possible ...
Researchers at the University of Bristol and Imperial College London have established a new model system that uses red blood cells grown in the laboratory to study how malaria parasites invade red ...
In addition, the study recommended production of antimalarial drugs that can disrupt rosette formation—the binding of malaria-infected red blood cell to uninfected ones, which is prominently seen in ...