A study led by University of Cincinnati Cancer Center researchers sheds new light on the mechanisms by which a major oncogene ...

Myc is a cancer-causing gene responsible for disrupting the normal 24-hour internal rhythm and metabolic pathways in cancer cells, found a team led by researchers from the Perelman School of ...

A study led by University of Cincinnati Cancer Center researchers sheds new light on the mechanisms by which a major oncogene ...

a team of Moffitt Cancer Center researchers demonstrated a possible alternative approach. They showed that MYC activates a downstream pathway that chemically modifies a protein called eIF5A ...

A study led by University of Cincinnati Cancer Center researchers sheds new light on the mechanisms by which a major oncogene ...

Cancer cells with elevated MYC expression often exhibit ... A current challenge is to identify additional synthetic lethal targets in these signaling pathways downstream of MYC. To date, both ...

A new review in Genes and Diseases explores the central role of MYC, a master regulatory protein, in the development and progression of cancer, spotlighting its potential as a multidimensional ...

a team of Moffitt Cancer Center researchers demonstrated a possible alternative approach. They showed that MYC activates a downstream pathway that chemically modifies a protein called eIF5A ...

Their attention centered on the MYC pathway because of its known role in prostate cancer. They discovered that another protein and transcription factor, NME2, works closely with MYC in advanced ...

In healthy cells, the MYC protein is critical to the transcription process, where genetic information is converted from DNA to RNA and, eventually, into proteins. But, in cancer cells, MYC becomes ...

In a new study published in the journal Cell Reports Medicine, a team of scientists at Baylor College of Medicine took a closer look at the molecular pathways metastatic cancer cells use and ...

For decades scientists have known a specific gene, called MYC, plays a crucial role in the proliferation of cancer cells. The gene is often over expressed in a variety of different tumors ...