Myc is a cancer-causing gene responsible for disrupting the normal 24-hour internal rhythm and metabolic pathways in cancer cells, found a team led by researchers from the Perelman School of ...

A new review in Genes and Diseases explores the central role of MYC, a master regulatory protein, in the development and progression of cancer, spotlighting its potential as a multidimensional ...

Cancer cells with elevated MYC expression often exhibit ... A current challenge is to identify additional synthetic lethal targets in these signaling pathways downstream of MYC. To date, both ...

a team of Moffitt Cancer Center researchers demonstrated a possible alternative approach. They showed that MYC activates a downstream pathway that chemically modifies a protein called eIF5A ...

They also show for the first time that the cancer cells' dependence on Myc -- a phenomenon called "oncogene addiction" -- is due to a pre-existing, self-regulatory pathway that, in the absence of ...

In healthy cells, the MYC protein is critical to the transcription process, where genetic information is converted from DNA to RNA and, eventually, into proteins. But, in cancer cells, MYC becomes ...

For decades scientists have known a specific gene, called MYC, plays a crucial role in the proliferation of cancer cells. The gene is often over expressed in a variety of different tumors ...

In a new study published in the journal Cell Reports Medicine, a team of scientists at Baylor College of Medicine took a closer look at the molecular pathways metastatic cancer cells use and ...