Human egg cells slow the activity of internal waste disposal systems as they mature, keeping metabolism low and damage at bay ...

Oocytes are long-lived cells that require specialized adaptations to maintain their fitness. This study shows that human ...

In human beings, egg cells need to survive for about five decades, much longer than most other cell types – and they may ...

Dr. Dominic Winter is researching how this “recycling center” works – and how defects in its composition play a role in cancer. The German Research Foundation has awarded Winter a Heisenberg ...

Think back to that basic biology class you took in high school. You probably learned about organelles, those little "organs" ...

The current understanding of lysosome biology and function is still evolving. There is a need for further characterization of these aspects that may provide critical information on the pathophysiology ...

A recent study published in Genes & Diseases reveals a novel role of XPR1 in promoting ovarian cancer growth by regulating autophagy and MHC-I ...

Researchers have discovered a powerful anti-aging pathway in roundworms, revealing how boosting the cells' lysosomes can help clear waste and promote healthy aging.

The lysosome-targeting chimera (LYTAC) approach, especially aptamer-based LYTAC, has shown promise for the targeted degradation of secreted and membrane proteins. However, the conventional monovalent ...