“If something happens and a molecule grows in abundance 200-fold in the lysosome, you would see only a two-fold increase if you look at the whole cell.” By isolating lysosomes from the rest of the ...

Investigators have discovered that outer mitochondrial membrane proteins regulate crosstalk between mitochondria and lysosomes, ... Scale bars, 0.5 μm. Credit: Journal of Cell Biology (2022 ...

Lysosomes digest excess or worn-out organelles, food particles, and engulf viruses or bacteria. The membrane around a lysosome allows the digestive enzymes to work at the 4.5 pH they require.

The study (‘Lysosome lipid signaling from the periphery to neurons regulates longevity’) published in Nature Cell Biology shows roundworm (Caenorhabditis elegans) lysosomes break down stored ...

Cellular and molecular biologists have discovered a new class of lysosomes that they refer to as 'tubular lysosomes.' This breakthrough could lead to medical therapies and treatments to slow -- or ...

Missing pathway in lysosome underlies newly discovered human disease Date: October 6, 2022 ... The team, led by Ming Li, assistant professor of molecular, cellular and developmental biology, ...

Think back to that basic biology class you took in high school. You probably learned about organelles, those little “organs” inside cells that form compartments with individual functions. For example, ...

Scientists at Baylor College of Medicine, the Howard Hughes Medical Institute (HHMI) and collaborating institutions report in the journal Nature Cell Biology that lysosomes in roundworms produce ...

More information: Hongwen Chen et al, Molecular basis of Spns1-mediated lysophospholipid transport from the lysosome, Proceedings of the National Academy of Sciences (2024). DOI: 10.1073/pnas ...