The lysosome is a small membrane bound organelle that can be found in most animal cells. It was once thought that these little sacs were like recycling centers that could take up cellular waste ...

A better understanding of lysosomal function may lead to new therapeutic strategies for these and other lysosome-related diseases. Now, in a new study published in the Journal of Cell Biology on ...

His review of the organelle's changing reputation was published in September's Journal of Cell Biology. As most high schoolers learn, the lysosome carries out waste disposal and recycling.

"There's the basic, fundamental science part of our work and then the biomedically relevant part, where we use our new knowledge of lysosome biology to see how it could be used for therapeutic ...

Lysosomes are membrane-bound organelles in cells that act as recycling centers—breaking down waste materials, damaged organelles, and unwanted molecules using powerful digestive enzymes ...

in Beijing who specializes in lysosomes and was one of the reviewers of the Nature Cell Biology article. Xiaochen Wang believes the work stands out because it was conducted in a living organism ...

Details of this work appeared August 7 in the Journal of Cell Biology, in an article entitled “Impaired JIP3-Dependent Axonal Lysosome Transport Promotes Amyloid Plaque Pathology.” By ...

Researchers at Duke-NUS Medical School and colleagues in Singapore have identified a protein that transports degraded membrane lipids out of lysosomes, cellular organelles that are the breakdown ...

cellular and developmental biology, discovered that if TMEM251 is defective, it fails to encode the pathway for the enzymes necessary for the correct function of lysosomes to travel inside the ...