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ANSWER: The term “lupus” generally means systemic lupus erythematosis (SLE), which is a systemic disorder (as its name suggests). So, by definition, it affects multiple systems of the body.

Find out more about lupus: the symptoms, types, causes, and who is at risk for developing this chronic autoimmune disease.

Dear T.S.B.: The term "lupus" generally means systemic lupus erythematosis (SLE), which is a systemic disorder (as its name suggests). So, by definition, it affects multiple systems of the body.