Lithium is the first-line therapy for the control of bipolar affective disorder. However, this monovalent cation can have several adverse effects on the kidney, namely tubular dysfunction ...

In some cases, taking lithium can lead to a form of diabetes insipidus. However, stopping the medication may reverse the condition. ... It may also contribute to a reduction in aquaporin-2, ...

Lithium interferes with the above cascade by decreasing the production and accumulation of cAMP, 17 downregulating expression of aquaporin-2 channels, 18 and decreasing the density of ADH ...

Aquaporin A/S (CSE: AQP) ("Aquaporin" or the "Company"), an innovative water technology company dedicated to rethinking water filtration with biotechnology, today announces the Annual Report for ...