These START domain proteins differ markedly from SCP2, however, in that they are selective for one, but not both, lipids. The tunnel in the MLN64-START structure ... areas of biology where START ...

Multi-C2 domain-containing ferlin proteins have key roles in membrane repair and vesicle trafficking, as well as links to ...

Nick Franks has challenged the accepted theory of what happens to our brains as we sleep, and he’s faced fierce and personal ...

Successful drug development for bioactive lipid targets requires a deep knowledge of the biology and pathobiology ... and metabolic profiles into the drug structure (Fig. 2).

A team of scientists has answered a long-standing question in cell biology, uncovering how the cell's main energy currency, ATP, is transported into the endoplasmic reticulum (ER). Disrupted energy ...

Researchers from the Göttingen Cluster of Excellence Multiscale Bioimaging (MBExC) have uncovered the 3D structure of the ...

The mammalian liver has an extraordinary regenerative capacity, capable of fully restoring its mass and function after injury ...

Researchers from the Göttingen Cluster of Excellence Multiscale Bioimaging (MBExC) have uncovered the 3D structure of the membrane proteins myoferlin and dysferlin using high-resolution cryo-electron ...

Oral 8-aminoguanine (8-AG) treatment preserved retinal structure and rod function in aged Fischer 344 rats, significantly ...

The Hidden Language of GlycansImagine a vast molecular conversation happening within and between cells—where sugar-based structures act as sophisticated messengers carrying critical biological ...

Mitochondria Are More Than Powerhouses—They’re the Motherboard of the Cell ...