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"Previous studies of ferroptosis have shown that there are mechanisms that control lipid peroxidation and that the cell membrane is damaged in the final stages of cell death. However, the origin ...
A molecule designed to activate iron locked up in organelles called lysosomes and thereby induce cell ... to encompass lipid–iron interactions that trigger membrane lipid peroxidation.
Hosted on MSN26d
Lipid Peroxidation in Lysosomes Unleashes Ferroptosis in TumorsThe duplication and division of cells is critical to keeping all multicellular organisms alive. But the opposite process is equally important: cell death. Controlled death of cells, or programmed ...
Lipid peroxides are oxidative degradation products of lipids, generated by a free radical chain ... to lipid peroxidation, which compromises the integrity and function of the cell membrane in ...
7don MSN
Plankton may be tiny, but they play an important role in the ocean. As the foundation of marine ecosystems, they support ...
Hosted on MSN28d
Lysosomal lipid peroxidation drives ferroptosis in cancer cellsIt is mediated by iron molecules, with the cell dying through the degradation of the phospholipid bilayer by oxidation, a process called lipid peroxidation. However, recent studies have shown that ...
In terms of physicochemical characteristics, CPMV NP is a plant-derived, replication-incompetent product that attracts innate immune cells to the TME. In contrast, CRT-NP is synthesized using lipids ...
Lipid membranes, which form the outer layer of cells, can be engineered to influence cellular functions. For example, ...
This fundamental study combines in vitro reconstitution experiments and molecular dynamics simulations to elucidate how membrane lipids are transported from the outer to the inner membrane of ...
Innovative delivery techniques, including high-tech nanoparticles and electroporationdevices, may convey more gene therapies into the clinic.
At ARVO 2025, in Salt Lake City, Utah, Peng Shang, PhD, talked about her presentation on how the Y402H polymorphism of ...
Study in mice shows how a host-elicited factor benefits gut immunological homeostasis by selectively targeting commensal ceramide molecules.
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