The lipid nanoparticles that caused an immune response interacted with the cell membrane without disrupting its signaling function.

A lipid nanoparticle, delineated in red, fuses with the bilayer membrane of an endosome to allow the RNA strand (squiggly grey line) to escape its nested enclosure. This lipid has a mixed internal ...

Scientists have discovered that the internal shape of tiny drug-delivery particles—called lipid nanoparticles—has a big impact on how well our cells absorb them, paving the way to more ...

First time physicists observed, quantified tiny nanoparticle crossing lipid membrane Date: November 2, 2016 Source: Global Oncology Summary: A new discovery may raise concerns about safety of ...

Lipid-based nanoparticles have emerged as highly useful particles in the pharmaceutical industry. However, their manufacturing involves complex processes and in-process monitoring, such as inline ...

A recent review looks at the molecular design of pH-sensitive cationic lipids and their applications for various tissues and cell types.

Researchers have developed a nanoparticle technology that can be used to stabilize membrane proteins so that their structure can be studied in a lipid environment. The method makes it possible to ...

A new method called NanoPOMP (nanoparticle promoted photochemical oxidation of membrane proteins) enables investigation of structural states of membrane proteins in their cellular environments.

Capstan Therapeutics scientists demonstrate that lipid nanoparticles can engineer CAR T cells within the body without laboratory cell manufacturing and ex vivo expansion.