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In multiple experiments, C-a16 lipids, which contain a phenol group, outperformed LNPs used in currently available mRNA ...

A group of University of Ottawa researchers have already shown how scientists can harness gene therapies to deliver ...

Tiny fat bubbles carrying gene therapy have successfully repaired DNA in the lungs and liver of animals with alpha-1 antitrypsin deficiency—a promising leap toward treating humans with this rare ...

Nanoemulsions, which are fine dispersions of oil and water phases, are particularly effective for incorporating hydrophobic ...

A new review highlights a powerful, cleaner route to produce ultra-clean, customizable nanoparticles—key building blocks for artificial sensory systems that mimic human perception and power emerging ...

What if mRNA vaccines could be made more powerful and less irritating? Scientists at the University of Pennsylvania have found a way to do just that—by tweaking a key molecule in the vaccine’s ...

Kiran Musunuru, a University of Pennsylvania cardiologist and leading gene-editing researcher, thinks it’s possible. Musunuru cofounded Verve Therapeutics, a company developing a therapy that uses ...

This is your definitive industry-led meeting to discover new lipid-based nanoparticle formulations and engineer delivery systems for emerging payloads beyond RNA for extrahepatic delivery.

Untargeted lipidomics analysis is widely performed using a variety of mass spectrometric methods. The original procedure, ...