Though a complex interplay of genes, diet, and environment contribute, 90% of cases share one thing in common: leptin resistance. In lean individuals, fat cells produce the hormone leptin, which ...

Most obese patients grow resistant to satiety signals from the hormone leptin. A new study shows that leptin sensitivity can be restored in mice, leading to weight loss. Worldwide obesity rates ...

Though a complex interplay of genes, diet, and environment contribute, 90% of cases have leptin resistance in common. In lean individuals, fat cells produce the hormone leptin, which suppresses ...

Though a complex interplay of genes, diet, and environment contribute, 90% of cases share one thing in common: leptin resistance. In lean individuals, fat cells produce the hormone leptin ...

Leptin is a hormone – a chemical messenger that helps different body parts work together. Leptin sends a signal to your brain that helps you feel full and less interested in food. You may hear ...

D: It's a hormone produced by fat cells. Leptin plays a key role in regulating appetite and metabolism. When you eat, fat cells release leptin, which then binds to receptors in a part of your ...

A significant aspect of obesity is the development of leptin resistance, primarily due to the inefficient transport of leptin across the blood-brain barrier and other mechanisms such as protein ...

One of those fat-to-brain signals is a hormone called leptin that regulates appetite. Decades ago, researchers hoped that a drug increasing leptin could suppress appetite and reduce obesity, but they ...

Leptin is a hormone. Those are chemical messengers that help different body parts work together. Leptin sends a signal to your brain that helps you feel full and less interested in food. You may ...

Most leptin supplements don’t actually contain the hormone leptin. Research is unclear whether these supplements can help you lose weight, but some studies suggest they can influence leptin ...

Opens in a new tab or window Share on LinkedIn. Opens in a new tab or window Personalized recombinant leptin treatment helped reverse severe, early-onset obesity in two children carrying rare ...

Here, we characterize two novel homozygous leptin variants that yielded antagonistic proteins in two unrelated children with intense hyperphagia, severe obesity, and high circulating levels of leptin.