Diagram of an antibody structure showing its key components, including antigen binding sites, variable and constant regions, light chains, and heavy chains. Image Credit: aiyoshi597/Shutterstock.com ...

The antibody development project was undertaken during her tenure at Memorial Sloan Kettering Cancer Center. In the study, five novel human anti-IL13Rα2 antibodies (KLG-1–5) were developed.

Antibody structure prediction has been widely used in many biological analyses 16,17,75. As example applications of the PIGS protocol, we have applied the PROCEDURE above to the modeling of the ...

The structure of the teleost Immunoglobulin M core provides insights on polymeric antibody evolution, assembly, and function. Nature Communications, 2023; 14 (1) DOI: 10.1038/s41467-023-43240-z; ...

Immunoglobulin G4 antibodies exhibit unusual properties with important biological consequences. We report the structure of the human full-length IgG4 S228P anti-PD1 antibody pembrolizumab, solved ...

More information: Mengfan Lyu et al, The structure of the teleost Immunoglobulin M core provides insights on polymeric antibody evolution, assembly, and function, Nature Communications (2023). DOI ...

Confocal microscopy image of human embryonic kidney cells. Nanoparticles filled with human immunoglobulin were delivered to the cells. The cell nucleus is blue, endosomes (which sequester ...

UDOT crews on Tuesday, April 23, 2024, respond to what the Utah Department of Transportation's traffic site labeled a "structure emergency" at a bridge on I-215 in Salt Lake City.

Bio-Rad Laboratories, Inc. (NYSE: BIO and BIO.B), a global leader in life science research and clinical diagnostics products, today announced the launch of its TrailBlazer™ Tag and TrailBlazer ...

Immunoglobulin M Monoclonal Gammopathies of Undetermined Significance and Indolent Waldenström's Macroglobulinemia Recognize the Same Determinants of Evolution Into Symptomatic Lymphoid Disorders: ...