The University of California, Davis, has been awarded just over $12 million from the National Institutes of Health under the third and final five-year phase of the Knockout Mouse Phenotyping Project, ...

The National Institutes of Health today awarded a set of cooperative agreements, totaling up to $52 million over five years, to launch the Knockout Mouse Project. The goal of this program is to ...

A knockout mouse is a laboratory mouse in which one or more genes have been turned off or "knocked out." To create a knockout mouse, scientists genetically engineer the animal by disrupting a gene ...

All the data is publicly available online for use in scientific research. Approximately 75% of protein-coding genes in the human genome have been catalogued in corresponding knockout mouse models.

The Knockout Mouse Phenotyping Program (KOMP2) sites at Baylor College of Medicine, Jackson Laboratory, and University of California, Davis, are collaborating with the International Mouse Phenotyping ...

The Centre Court crowd that flocked in expecting a cat-and-mouse contest exited with an anti-climatic straight-sets knockout ...

The knockout mice showed distinctly different characteristics in all of them. Related Stories Inhalable gene therapy tested for cystic fibrosis treatment in the UK and Europe ...

A drug commonly used to treat type 2 diabetes may reduce excess fluid in the brains of patients with hydrocephalus, which could help treat the disease less invasively than current treatments, ...

New research shows that retinal neurons can rewire to preserve vision in retinitis pigmentosa, a genetic disease causing blindness.

Born as a pandemic diversion in 2020, “Knockout” is finally a fully baked dance performance, premiering with a two-week run kicking off the spring edition of Steppenwolf’s LookOut Series.

Cellular communication between neurons within our brain is complex and busy, much like a USPS mailroom.To keep things running ...

To generate a tissue specific knockout mouse, researchers breed a mouse bearing a Cre transgene under a tissue- or cell-type specific or inducible promoter (A) with a homozygous floxed mouse (B). The ...