The ability of protein kinases to transfer a phosphate group to target proteins plays an important role in many cellular ...

Comparison with various high-throughput phosphorylation mapping studies showed limited overlap between the kinase phosphorylation interactions and kinase protein–protein interactions, suggesting ...

Pfizer drug Braftovi achieved statistically significant and clinically meaningful improvement in overall survival for colorectal cancer patients in a Phase 3 clinical trial. The results will be ...

This work is published in Nature Cell Death & Disease in the paper, “ Opposing roles for GSK3β and ERK1-dependent phosphorylation of huntingtin during neuronal dysfunction and cell death in ...

Whether you need a GIF for social media, presentations, or just for fun, this straightforward method works for all kinds of images and animation needs. Here's how to create your own custom GIFs ...

Explore how kinase inhibitors are transforming neurodegenerative disease research through targeted therapy.

A Parkinsonian mystery—how PINK1 locks onto malfunctioning mitochondria—now has a structural solution. Researchers at the University of Melbourne led by Sylvie Callegari, Alisa Glukhova, and David ...

Here is how to automatically play animated GIFs in Google Image search results using a free Google GIFs Chrome Extension extension.

Discover how next-generation kinase inhibitors are transforming clinical therapy byovercoming resistance and enhancing treatment efficacy.

ING5 inhibits aerobic glycolysis of lung cancer cells by promoting TIE1-mediated phosphorylation of pyruvate dehydrogenase kinase 1 at Y163 ...

A research group has discovered that in mammals, a protein kinase A (PKA) promotes wakefulness, while protein phosphatase 1 (PP1) and calcineurin promote sleep. This study revealed that the ...