Plant phototropism—directional growth in response to light—serves as a key adaptive mechanism, optimizing photosynthesis and ...

The ability of protein kinases to transfer a phosphate group to target proteins plays an important role in many cellular ...

Jak2 is a 130 kDa tyrosine kinase that is important in a number of cellular signaling pathways. Its function is intrinsically regulated by the phosphorylation of a handful of its 49 tyrosines. Here, ...

Protein phosphorylation is one of the most abundant reversible post-translational modifications in eukaryotes. It is involved in virtually all cellular processes by regulating protein function, ...

The catalytic (C) subunit of cAMP-dependent protein kinase (PKA) is a serine/threonine kinase responsible for most of the effects of cAMP signaling, and PKA serves as a prototype for the entire kinase ...

Comparison with various high-throughput phosphorylation mapping studies showed limited overlap between the kinase phosphorylation interactions and kinase protein–protein interactions, suggesting ...

Ryanodine receptor (RyR) phosphorylation by protein kinase A (PKA) may be important in modulating resting sarcoplasmic reticulum (SR) Ca2+ release, especially in heart failure. However, clear cellula ...

In two-component systems, unlike STTK pathways, phosphorylation levels of downstream components are not directly correlated with the level of kinase phosphorylation.

Miss the '90s? Now You Can Search Old-School GIFs Like a Pro The Internet Archive's vintage GIF search engine, GifCities, now supports keyword searches and searches by dimensions.

In response to diverse stress stimuli, eukaryotic cells activate a common adaptive pathway, termed the integrated stress response (ISR), to restore cellular homeostasis. The core event in this pathway ...