The ability of protein kinases to transfer a phosphate group to target proteins plays an important role in many cellular ...

Network Integration Efforts to characterize the phosphorylation network have also been aimed at integrating the yeast phosphorylation network with other types of interaction data. These efforts ...

Although the function of the p42/p44 mitogen-activated protein (MAP) kinase pathway in long-term potentiation at hippocampal CA3–CA1 synapses has been well described, relatively little is known ...

Protein kinase C-θ (PKC-θ) is essential for mature T cell activation; however, the mechanism by which it is recruited to the TCR signaling machinery is unknown. Here we show that T cell ...