The gene therapy vector, produced under UK regulatory approval, delivered the AIPL1 coding sequence using a human rhodopsin kinase promoter ... the PopCSF touchscreen assay and steady-state ...

Hematopoietic and lymphocytic neoplasms (HLNs) are a diverse group of malignancies affecting blood and lymphatic systems, with outcomes varying from ...

The American Association for Cancer Research (AACR) today announced its newly elected 2025 class of Fellows of the AACR Academy.

This new cryo-EM structure represents a remarkable advance in our understanding of how human PINK1 is stabilized” said ...

Cancer cells have an insatiable appetite for energy as they multiply more rapidly than normal cells. Greedy cancer cells hijack various cellular functions to find and exploit energy and other ...

Studies of breast cancer cells have highlighted the importance of a type of CK called ubiquitous mitochondrial creatine kinase (uMtCK). Scientists at Sanford Burnham Prebys and the Mayo Clinic ...

Macbecin II was identified as a compound that upregulates MHC-I expression, enhancing immune-mediated cancer cell killing. In ...

The FDA acknowledges the necessity of immunogenicity assays to assess immune responses to components of oligonucleotide therapeutics, particularly those with carriers or conjugates.

This valuable study identifies a protein called adenosine deaminase-related growth factor (ADGF) as a key regulator of tip formation in the slime mold Dictyostelium discoideum. The authors ...