Intervertebral disc degeneration (IDD), a common cause of chronic low back pain, strongly impacts daily life. Although previous studies have identified certain biomarkers indicating IDD, comprehensive ...

Announcing a new article publication for BIO Integration journal. Imbalances in the intestinal microbiome are closely ...

KEGG pathway analysis showed significant enrichment in pathways like plant hormone signal transduction, starch metabolism, and phenylpropanoid biosynthesis (Figure 2 D), suggesting that these pathways ...

Gene Ontology (GO) functional enrichment analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis were performed with a significance threshold of p ≤ 0.05. The analyses ...

By Pooja Toshniwal Paharia New research uncovers gut microbiome links to lupus and IBD, pointing to potential biomarkers and ...

Furthermore, the gene sets omitted from KEGG were not considered in the pathway analysis owing to insufficient coverage of genes by known biological pathways, which is the common limitation of the ...

Abstract The reconstruction of complete microbial metabolic pathways using ‘omics data from environmental samples remains challenging. Computational pipelines for pathway reconstruction that utilize ...

KEGG hosts a series of experimentally verified and manually crafted biological pathways procured from various species and, most notably, all pathways can be externally downloaded as a network map ...

"Pathway_Feature_Identification.py" is a script for analyzing microbial genomic data, identifying antimicrobial resistance-associated pathways using KEGG data, and applying logistic regression for ...

The quick question is: when performing KEGG enrichment analysis, should genes that have no KEGG identifier/annotation be excluded from the Wilcox test comparing p-values of genes in pathway vs genes ...

Using benchmarks constructed from the KEGG pathway database we found that clustering can be beneficial by increasing the sensitivity of pathway analysis methods and by providing deeper insights of ...