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Patients with type 2 diabetes mellitus are at a higher risk of developing heart failure compared with the healthy population. In recent landmark clinical trials, sodium-glucose co-transporter 2 (SGLT2 ...
The application of machine learning algorithms to predict the mechanism of action (MoA) of drugs can be highly valuable and enable the discovery of new uses for known molecules. The developed methods ...
Outstanding questions on the prothrombotic potential of lipoprotein (a) remain to be answered, particularly the mechanisms by which lipoprotein (a) can impact thrombosis beyond a role in fibrinolysis ...
In this GEN webinar, Dave Lahr, PhD, Senior Director of Bioinformatics at Foghorn Therapeutics, discusses chromatin regulation and epigenetic mechanisms that shape transcriptional responses to ...
Sitagliptin monotherapy significantly improved hemoglobin A1c, fasting plasma glucose (FPG) and 2-h postprandial glucose (PPG) compared with placebo ( Table 1 ).
Fermented-litchi polysaccharide (Lzp) has been demonstrated to enhance the production of exopolysaccharides (EPS) in Weissella confusa in our previous study. To elucidate the underlying mechanisms, ...
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