News

Atomic-level view of plant cell death enzyme offers path to safer crop protection
In a discovery three decades in the making, scientists at Rutgers and Brookhaven National Laboratory have acquired detailed ...
Immune restraint through the ages: PD-1 pathway traced to sharks
In 1992, graduate student Yasumasa Ishida discovered PD-1, marking the beginning of a journey that would make this molecule a ...
New findings reveal how the heart is organized from the earliest stages of embryonic development
A study published today in the journal Developmental Cell uncovers new insights into how the heart forms during the earliest stages of embryonic development.
C&EN7d
Beyond Blocking: Engineering RNAi-Mediated Targeted Immune Checkpoint Nanoblocker Enables T-Cell-Independent Cancer Treatment
Molecular Science and Biomedicine Laboratory, State Key Laboratory of Chemo/Bio-Sensing and Chemometrics, College of Chemistry and Chemical Engineering, Aptamer Engineering Center of Hunan Province, ...
Variety21d
‘Elsbeth’ Team Breaks Down That Big Jailhouse Musical Number, the Finale’s Goodbye to Kaya and the Return of All Those Murderers
SPOILER ALERT: This post contains spoilers from “Ramen Holiday,” the Season 2 finale of “Elsbeth,” now streaming on Paramount+. All it took was a little razzle dazzle and a stint in prison ...
C&EN21d
Mechanism of Juglone-Induced Cell Cycle Arrest and Apoptosis in Ishikawa Human Endometrial Cancer Cells
School of Food and Biological Engineering, Hefei University of Technology, Hefei 230009, People’s Republic of China Anhui Province Key Laboratory of Functional Compound Seasoning, Anhui Qiangwang ...
Cancer Research28d
TLR5 Signaling Causes Dendritic Cell Dysfunction and Orchestrates Failure of Immune Checkpoint Therapy against Ovarian Cancer
1Department of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, Virginia.
The EMBO Journal29d
mTOR controls ependymal cell differentiation by targeting the alternative cell cycle and centrosomal proteins
We demonstrate that mTORC1 inhibition by rapamycin preserves the progenitor pool by reinforcing quiescence and preventing alternative cell cycle progression for centriole amplification. Overexpressing ...
Forbes1mon
Managing Change Throughout The Life Cycle Of A Business
Years ago, I was introduced to the Adizes Organizational Life Cycle model, which maps the evolution of businesses from infancy to prime and, if mismanaged, into inevitable decline. Seeing this ...