Objective In this investigation, we examined the efficacy of glycine administration and its potential enhancement in interferon-α (IFN-α) antiviral efficacy to stimulate hepatocyte proliferation to ...

Thunderstorms are known to generate gamma rays, the highest energy radiation on Earth. But pinning the burst to a specific bolt is new.

Summary for Physicians: Choosing Between Hydroxyurea and Interferon in PV The decision between hydroxyurea (HU) and interferon (IFN) for cytoreductive therapy in polycythemia vera (PV) is influenced ...

PharmaEssentia Reaffirms its Commitment to Robust and Reliable Access to Interferon Therapies Amid Global Supply Challenges January 02, 2025 10:03 AM Eastern Standard Time ...

Interferon gamma-1b (Actimmune) treats chronic granulomatous disease, which affects the way your immune system works, and severe malignant osteopetrosis, which affects your bones.

Interferon-gamma (IFNγ) action on tissue macrophages stimulates the release of the cytotoxic chemokine CXCL9. It was investigated if this mechanism may be an independent sepsis endotype.

The prognostic impact of transforming growth factor beta 2 (TGFB2) mRNA levels, in conjunction with interferon-gamma receptor activation of interferon regulatory factor 5 (IRF5) and expression of ...

To corroborate the interferon-γ responses found in patients with APS-1, we performed immunologic evaluations of wild-type and Aire−/− mice and in situ hybridization evaluations of wild-type ...

In mice with an intact immune system, alpha-synuclein overexpression in the mouse model resulted in increased numbers of CD4+ T-cells that were also positive for the transcription factor T-bet, along ...

Type 1 interferons (IFNs) play a central role in the development and disease course of systemic lupus erythematosus (SLE).

A histone-like protein of the adenovirus binds the A-box of host protein HMGB1 to repress the host immune response and promote infection.

People with ALS due to mutations in the FUS gene may benefit from interferon-gamma therapy to delay disease onset and/or progression, an early cell-based study says.