In the present study we employed microfabricated surfaces to capture T-cells from minimally processed human blood, arrange these cells into a single cell array, and then detect interferon (IFN)-γ ...

1 Department of Paediatrics, The University of Melbourne, Royal Children's Hospital Melbourne, Australia 2 Infectious Diseases Unit, Department of General Medicine, Royal Children's Hospital Melbourne ...

Introduction In Hong Kong, tuberculin skin test (TST) with a 15 mm cut-off was used at 0 and 3 months for contact screening, but half of future tuberculosis cases might be missed. Follow-on interferon ...

However, current diagnostic tools, such as interferon-gamma release assays (IGRAs) and tuberculin skin tests (TSTs ... Using this refined feature set, we identified IGRA/TST + contacts whose blood ...

In the present follow-up study, we investigated the effect of the addition of Mycobacterium leprae antigens on interferon-gamma (IFN-γ ... The detection limit of the assays was 8 pg/mL for both IFN-γ ...

This study assessed the prevalence of LTBI in PLWH using the interferon-gamma release assay (IGRA) and the impact of the 3HP regimen (isoniazid [INH]/rifapentine [RPT]) as prophylactic treatment.

aSheffield Centre for Health and Related Research (SCHARR), School of Medicine & Population Health, University of Sheffield, UK bThe Research Department of Primary Care and Population Health, ...