I Biodexa Pharmaceuticals PLC (“Biodexa” or the “Company”) (Nasdaq: BDRX), a clinical stage biopharmaceutical company developing a pipeline of ...

The unfolded protein response (UPR) is a crucial signaling network that preserves endoplasmic reticulum (ER) homeostasis, impacting both health and disease. When ER stress occurs, often due to an ...

Growth Hormone-Releasing Peptide-2 (GHRP-2) is a synthetic hexapeptide that has garnered significant attention in the ...

Insulin efsitora alfa (investigational once-weekly basal insulin): In another ADA-sponsored symposium, Lilly will share results from the QWINT-1, QWINT-3 and QWINT-4 Phase 3 trials, which evaluated ...

Ma and colleagues explained that the “C-peptide concentration in peripheral blood is generally considered to be the most suitable marker of insulin secretion ... Multiple cell signalling pathways of ...

Biodexa Announces Recruitment of First Patient in Phase 2 Study of Tolimidone in Type 1 Diabetes Biodexa Pharmaceuticals PLC ("Biodexa" or the "Company") (Nasdaq: BDRX), a clinical stage ...

Results of the study at four weeks after cell transplantation demonstrate the survival and function of pancreatic beta cells as measured by the presence of circulating C-peptide, a biomarker ...

The peptide’s structure has been optimized to resist enzymatic degradation, allowing for a longer half-life compared to its endogenous counterpart. By activating GLP-1 receptors, Semaglutide is ...

Insulin signaling pathway is conserved across species ... DILP1-7 are structurally similar to preproinsulin, with a predicted signal peptide, B chain, C peptide, and A chain. CHICO is an adaptor ...

Our previous work in C. elegans indicates that germline development requires coordinated activities of insulin/IGF-1 signaling (IIS ... We found that IIS activates the expression of intestinal peptide ...