Background and aims: A characteristic feature of Crohn’s disease (CD) is mesenteric adipose tissue hypertrophy. Mesenteric adipocytes or specific proteins secreted by them may play a role in the ...

Sceptrin, a natural compound produced by various marine sponges, was tested for its effect on cell motility. We report for the first time that sceptrin inhibits cell motility in several cancer cell ...

Plasminogen (Plg), the pro-enzyme of the serine-protease plasmin, is known for its role in cleaving blood clots within the fibrinolytic pathway. More recently, Plg has been reported to associate with ...

Objectives: CEPT1, choline/ethanolamine phosphotransferase 1, is an important mediator of de novo phospholipogenesis and is essential for endothelial cell (EC) survival. CEPT1 catalyzes the synthesis ...

Mechanistic investigation revealed that tetramethoxystilbene 4o blocks the oligomerization of apoptosis-associated speck-like protein (ASC), which is the vital step in the formation of NLRP3 ...