The Food and Drug Administration (FDA) has accepted for Priority Review the Biologics License Application (BLA) for sibeprenlimab for the treatment of immunoglobulin A nephropathy (IgAN ...

Approval was based on results from the Phase III ALIGN study, which demonstrated a significant reduction in proteinuria at 36 weeks in patients with primary immunoglobulin A nephropathy. The FDA ...

Atrasentan reduced urine protein-to-creatinine ratio by 38% compared with 3% for placebo at week 36. The Food and Drug Administration (FDA) has granted accelerated approval to Vanrafia ...

Findings showed after 52 weeks, significant improvements in 2MWD and 6MWD were seen with Flebogamma 5% DIF 1mg/kg compared with placebo. Topline data were announced from a phase 2/3 trial ...

Gut IgA functionally interacts with systemic IgG to enhance antipneumococcal vaccine responses. Science Advances , 2025; 11 (7) DOI: 10.1126/sciadv.ado9455 Cite This Page : ...

Examples of allergens include mold, pollen, animal dander, and dust mites. When a person has allergies, the white blood cells produce an antibody called immunoglobulin E (IgE) in response to one or ...

The agreement involves an anti-immunoglobulin E monoclonal antibody designed to treat various allergic conditions. Credit: Volha_R / Shutterstock. RAPT Therapeutics and Shanghai Jemincare ...

Immunoglobulins are antibodies, and the five different classes of these antibodies are IgG, IgA, IgM, IgD and IgE. Through their biological function of binding antigens, antibodies facilitate the ...

Dan Ige was about as mentally removed from a fight as one could get on a Saturday afternoon. He'd just spent the last hour on a massage table at his home in Las Vegas. Deep-tissue massage ...

A positive rubella IgG test indicates immunity to rubella, meaning that the pregnant person and the fetus cannot contract this virus. If a person contracts rubella, also known as German measles ...

San Antonio's Mare e Monte is a straightforward Italian venue with beautifully executed seafood. This agreeable restaurant, whose name evokes the sea and mountains between Italy and Albania ...

Amid the hustle of reds poured into wine glasses, servers bringing out freshly baked bread, and the endless chatter of patrons glancing over Mare e Monte's Italian menu with an Albanian twist in ...