We previously reported the development and preclinical characterisation of MAR001, an ANGPTL4 inhibitory antibody. Here, we report a comprehensive safety assessment of ANGPTL4 inhibition, including ...

The first step of activation of the classical complement pathway involves the binding of the globular C1q domain (gC1q) to the antigen-bound IgG or IgM. To improve our understanding of the mechanism ...

The concentration of IgG and IgA in cervical mucus was determined by radial immunodiffusion essay (Bovine IgG Test Kit and Bovine IgA Test Kit, Eurovet Veterinaria S.L., Madrid, Spain), following the ...

Pfizer is paying $1.25 billion upfront in a licensing pact with 3SBio, gaining access to the Chinese biotech’s PD-1/VEGF bispecific antibody for various solid tumors, the pharma revealed Monday ...

Pfizer has signed a worldwide licensing agreement, excluding China, with biopharmaceutical company 3SBio to develop, manufacture and commercialise bispecific antibody targeting programmed cell death ...

Mature antibodies (Abs) that are exquisitely specific for virtually any foreign molecule may be produced by affinity maturation of naïve (or germline) Abs. However, the finite number of germline Abs ...

Long working hours might not just be bad for you, they could also be altering the structure of your brain, a new study suggests. The research was conducted by two scientists at South Korea’s ...

Long working hours may alter the structure of the brain, particularly the areas associated with emotional regulation and executive function, such as working memory and problem solving, suggest the ...

Timing and Outcomes of Palliative Care Integration Into Care of Adolescents and Young Adults With Advanced Cancer The advent of next-generation antibody-drug conjugates (ADCs), particularly ...

Eli Lilly licensing AIchemab’s ALS antibody therapy in $415M deal Eli Lilly licensing AIchemab’s ALS antibody therapy in $415M deal. ATLX-1282 came from research into mutations tied to frontotemporal ...