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Argenx (NASDAQ:ARGX) is one of the best biotech stocks to invest in now. On June 20, Argenx announced that the European ...
With 18 monoclonal antibody (mAb) products currently on the market and more than 100 in clinical trials, it is clear that engineered antibodies have come of age as biopharmaceuticals. In fact, by ...
Antibody fragments can be used to make antibody-drug conjugates. Here’s advice on how to produce the fragments themselves. Antibody-drug conjugates (ADCs) have great potential as targeted cancer ...
Antibody fragments have been used to aid structural analysis of complex macromolecules that are otherwise crystallization-resistant. However, there are issues such as stability, ...
Researchers at the Max Planck Institute for Molecular Genetics have developed a novel synthetic micropeptide termed the ...
ITHACA, N.Y. -- A novel cancer therapeutic, combining antibody fragments with molecularly engineered nanoparticles, permanently eradicated gastric cancer in treated mice, a multi-institutional ...
Our study shows how a small antibody fragment can block fertilization by targeting ZP2, a key protein in the outer layer of the egg that is involved in both sperm binding and blocking polyspermy." ...
The fragments at the antibody tips (shown in circles), called variable domains, stick to parts of pathogens or toxins, whatever substance is recognized as foreign to the body.
In recent years, there is increasing use of antibody fragments as crystallization chaperones to aid the structural determination of otherwise "uncrystallizable" or "undruggable" target proteins.