A new study published in Nature Neuroscience has identified a brain circuit in mice that overrides basic needs like hunger or ...

A high-fat diet can promote overweight and increase the risk of metabolic diseases, such as diabetes. In mice brains, this leads to measurable changes in the region of the hypothalamus. However ...

A new study in mice points to a different player in the aging process: a special population of cells in the hypothalamus, a tiny region of the brain.

On the other hand, a different 2017 study in mice concluded that a diet high in both fat and sugar — not just fat — caused inflammation of the hypothalamus.

Overall, the findings gathered by the researchers suggest that the risk preference of mice during reward-based decision-making tasks is supported by functionally different hypothalamus–habenula ...

Researchers have discovered the mechanism by which a cluster of astrocytes, specialized brain cells, in the hypothalamus cause obesity in mice. Their study also identified a drug that inhibited ...

One route they are studying involves supplementing mice with eNAMPT, the enzyme produced by the fat tissue that returns to the brain and fuels the hypothalamus, among other tissues.

A new study in mice found a “phone line” between fatty tissues and a group of neurons inside the hypothalamus—a region at the bottom of the brain that controls basic bodily functions such as ...

They also used a technique to directly activate these specific neurons in the hypothalamus of old mice, and they observed similar anti-aging effects.

In mouse models, Zhu and colleagues found that pantothenate was responsible for the secretion of GLP-1 and subsequent secretion of FGF21, a liver hormone that acts directly on the hypothalamus ...

A new study in mice proposes for the first time a novel factor that drives aging processes. The authors of the study report that a reduction in the protein menin in the brain’s hypothalamus ...

Neurons whose activity mirrors fighting by other mice were identified in the male mouse hypothalamus and were functionally important for aggression.