HYDROXYPROLINE, a nonessential imino acid, occurs in the body almost exclusively in collagen, where it accounts for 13 per cent of the total amino acids.1 Man excretes hydroxyproline in the urine i ...

Table 1 shows the total twenty-four hour urinary excretion in a group of 12 normal volunteers. The mean excretion for the male group was 28.1 mg. (S.D. ± 8.5, with a range of 20.6 to 41.0) and ...

Structural basis for the recognition of hydroxyproline in HIF-1α by pVHL. ... also has a ligand-dependent activation function. But, there has been a problem — the GR LBD has been tricky to ...

Therefore, the team assumed that increased hydroxyproline levels might be the cause of joint hypermobility. By various estimates, this disorder is found in 15% to 50% of young ASD patients.

There is no direct evidence, so far, of the existence of a peptide which, as a precursor of collagen, should contain the typical collagen imino-acid hydroxyproline.