However, spironolactone was associated with an increased risk of hyperkalemia, with 123 events in the spironolactone-treated group vs 80 in the placebo group (HR, 1.54; 95% CI, 1.07-2.22).

Of these HF post-AMI patients, 1,016 (10.9%) used spironolactone after the diagnosis was received, while only 686 (7.4%) patients used spironolactone in the first year following the diagnosis.

Mechanism of action describes the process by which a molecule, such as a drug, functions to produce a pharmacological effect. A drug’s mechanism of action may refer to its effects on a ...

"Certain medications, such as corticosteroids or some diuretics, such as hydrochlorothiazide (HCTZ) and chlorthalidone, can also contribute to high blood sugar," notes Dr. Connor. Wellness ...

The first meeting of the China-US economic and trade consultation mechanism opened in London on Monday, Xinhua News Agency reported. Chinese Vice Premier He Lifeng, also a member of the Political ...

Key Takeaways Common blood pressure medications include diuretics, ACE inhibitors, ARBs, calcium channel blockers, and beta-blockers. There are many treatment options, so your healthcare provider can ...

Current toxicant identification mainly relies on subjective and blind toxicity testing and compound screening. This could overlook the sensitive toxicity end point and key toxicants due to the random ...