Amgen's long-acting experimental obesity drug MariTide needs to be given at a low starting dose to limit side effects like ...

A 6-week randomized trial found that tirzepatide significantly reduced energy intake, appetite, and cravings in adults with ...

In Part A, single ascending doses up to 25 mg were tested; in Part B, multiple ascending doses over 10 days up to 12 mg were tested; and in Parts C and D different multiple ascending dose protocols ...