INmune Bio's XPro1595 targets soluble TNF for Alzheimer's. Phase 2 results could reshape inflammatory disease treatment.

Chloride intracellular channel-4 (CLIC4) is regulated by p53 and tumor necrosis factor-α (TNF-α), it is linked ... with bovine serum albumin was used as negative control and human melanoma tissue ...

Objective To assess the effects of treatment with antitumour necrosis factor (TNF) agents, methotrexate, or other non-biological disease-modifying antirheumatic drugs (DMARDs) on cardiovascular event ...

Aldosterone Abrogates Nuclear Factor κB–Mediated Tumor Necrosis Factor α Production in Human Neutrophils via the Mineralocorticoid Receptor. Astrid Bergmann, Claudia Eulenberg, Maren Wellner, Susanne ...

Objectives Intraplaque angiogenesis and inflammation are key promoters of atherosclerosis and are mediated by the alpha-V beta-3 (αvβ3) integrin pathway. We investigated the applicability of the ...

Cite this: Technology Insight: Utility of TNF-Alpha-Based Isolated Limb Perfusion to Avoid Amputation for Irresectable Extremity Tumors - Medscape - Feb 01, 2006. Summary and Introduction ...

Abstract: Accurate and real-time monitoring of biomarker proteins, such as Tumor Necrosis Factor (TNF) alpha, plays a vital role in early disease diagnosis, effective treatment design, and ...

Kavanaugh A, McInnes I, Mease P, et al. Golimumab, a new human tumor necrosis factor alpha antibody, administered every four weeks as a subcutaneous injection in psoriatic arthritis: twenty-four-week ...

Marked synergism between tumor necrosis factor-alpha and interferon-gamma in regulation of keratinocytederived adhesion molecules and chemotactic factors. J Clin Invest. 1990;85:605- 8. 10. Gomi T, ...

Tumor necrosis factor alpha (TNF-α) has been a central focus in immunology for over three decades. ... TNF-α Across Species: Human and Animal Health in Parallel .